Clinical Implications of Fibroblast Activation Protein in Patients with Colon Cancer
نویسندگان
چکیده
منابع مشابه
Clinical implications of fibroblast activation protein in patients with colon cancer.
PURPOSE Human fibroblast activation protein (FAP)/seprase is a 97-kDa surface glycoprotein expressed on tumor associated fibroblasts in the majority of epithelial cancers including colon adenocarcinomas. FAP overexpression in human tumor cells has been shown to promote tumor growth in animal models, and clinical trials targeting FAP enzymatic activity have been initiated. The primary objective ...
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چکیده ندارد.
15 صفحه اولClinical and Prognostic Implications of Transcription Factor SOX4 in Patients with Colon Cancer
Colon cancer is one of the most common malignant cancers worldwide but the current therapeutic approaches for advanced colon cancer are less efficient. This study investigated associations between the expression of nuclear transcription factor SOX4 and various clinicopathologic parameters as well as patients' survival. Expression levels of nuclear SOX4 were analyzed by immunohistochemistry; the...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2007
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-06-1746